Researchers began experimenting with organ transplantation on animals and humans in the 18th century. Over the years, scientists have experienced many failures, but by the mid-20th century, they were performing successful organ transplants. Transplants of kidneys, livers, hearts, pancreata, intestine, lungs, and heart-lungs are now considered routine medical treatment.

In the last 20 years, important medical breakthroughs such as tissue typing and immunosuppressant drugs have allowed for a larger number of organ transplants and a longer survival rate for transplant recipients. The most notable development in this area was Jean Borel's discovery of an immunosuppressant drug called Cyclosporine in the mid-1970s. This drug was approved for commercial use in November 1983.

Unfortunately, the need for organ transplants continues to exceed the supply of organs. But as medical technology improves and more donors become available, the number of people who live longer and healthier lives continues to increase each year.

Transplant Milestones in the United States and Canada

1954

First successful kidney transplant*
Dr. Joseph E. Murray, Brigham & Women's Hospital, Boston, MA

1966

First successful pancreas/kidney transplant
Drs. Richard Lillehei, William Kelly, University of Minnesota, Minneapolis, MN

1967

First successful liver transplant*
Dr. Thomas Starzl, University of Colorado Health Sciences Center, Denver, CO

1968

First isolated pancreas transplant
Dr. Richard Lillehei, University of Minnesota, Minneapolis, MN

1968

First successful heart transplant
Dr. Norman Shumway, Stanford University Hospital, Stanford, CA

1981

First successful heart-lung transplant
Dr. Bruce Reitz, Stanford University Hospital, Stanford, CA

1983

First successful single lung transplant*
Dr. Joel Cooper, Toronto Lung Transplant Group, Toronto General Hospital, Toronto Canada

1986

First successful double lung transplant*
Dr. Joel Cooper, Toronto Lung Transplant Group, Toronto General Hospital, Toronto Canada

1989

First successful living-related liver transplant
Dr. Christoph Broelsch, University of Chicago Medical Center, Chicago, IL

1990

First successful living-related lung transplant
Dr. Vaughn A. Starnes, Stanford University Medical Center, Stanford, CA

*Transplant was the first of its kind in the world


This Web site is designed, developed, and maintained by the United Network for Organ Sharing (UNOS) under contract with the U.S. Department of Health and Human Services (HHS) and the Health Resources and Services Administration (HRSA). We are committed to meeting 508 standards and making this site accessible to all users. If you are using an accessibility reader and you are experiencing technical issues with this page, please contact Patient Services at (888) 894-6361.
Text SizeIncrease Font SizeDecrease Font Size